3.0T磁共振弥散加权成像、表观弥散系数、波谱成像联合血清前列腺特异性抗原在前列腺癌诊断中的效能分析

Efficacy analysis of 3.0T magnetic resonance diffusion-weighted imaging,apparent diffusion coefficient,spectral imaging combined with serum prostate specific antigen in the diagnosis of prostate cancer

目的分析前列腺癌诊断中联合3.0T磁共振PSA(血清前列腺特异性抗原)、MRS(波谱成像)、ADC(表观弥散系数)、DWI(弥散加权成像)的应用效果。方法 2016年6月～2018年6月于我院收治的前列腺癌与前列腺增生患者中分别选取60例为研究对象,均经手术病理或者穿刺活检确诊,治疗前或者术前均接受MRI检查,对其PSA、MRS、ADC、DWI资料进行收集,由3名具有丰富经验的高资历医师采用盲法阅片,对比诊断结果与病理结果之间的差异。结果与其他两种诊断方式相比,PSA+MRS+ADC+DWI+MRI在前列腺癌诊断中的准确度、特异度、敏感度更高,假阴性率、假阳性率更低,差异有统计学意义(P <0.05)。结论前列腺癌诊断中联合PSA、MRS、ADC、DWI以及常规MRI的效果显著。

Objective To analyze the application effect of combined 3.0T magnetic resonance PSA (serum prostate specific antigen),MRS (spectral imaging),ADC (apparent diffusion coefficient) and DWI (diffusion weighted imaging) in the diagnosis of prostate cancer. Methods 60 patients with prostate cancer and benign prostatic hyperplasia enrolled in our hospital from June 2016 to June 2018 were diagnosed by surgical pathology or biopsy.MRI was performed before or before surgery,and the data of PSA,MRS,ADC and DWI were collected.Three highly qualified physicians with rich experience read the film by blind method, and the differences between diagnosis results and pathological results were compared. Results Compared with the other two diagnostic methods,PSA+MRS+ADC+DWI+MRI had higher accuracy,specificity and sensitivity in the diagnosis of prostate cancer,and lower false negative rate and false positive rate,with significant difference (P<0.05). Conclusion The combination of PSA,MRS,ADC,DWI and conventional MRI in prostate cancer diagnosis is significant.