贻贝启发蒙脱石-银/聚乳酸抗菌膜的制备及其性能

Preparation and Properties of Mussel-inspired MMT-AgNPs/Polylactic Acid Composite Antibacterial Film

受自然界贻贝粘附现象的启发,将聚多巴胺(PDA)作为二次反应平台,绿色合成了一种纳米银(Ag NPs)负载蒙脱石(MMT-Ag NPs)复合抗菌颗粒,通过溶剂挥发法将聚乳酸(PLA)和MMT-AgNPs共混,制备了复合抗菌膜(PLA/PDA/MMT-AgNPs)。利用FTIR、XRD、TEM和TGA对MMT-Ag NPs的物质组成、物相结构、微观形貌、热稳定性进行了测定。对所制备的PLA/PDA/MMT-AgNPs复合抗菌膜的微观形貌、物理性能和抗微生物活性进行了考察。结果表明:PDA成功地对MMT进行了改性,PDA改性的MMT仍保持原来的物相结构,Ag NPs在MMT表面成功负载,负载的质量分数达到12.2%。PLA/PDA/MMT-AgNPs复合抗菌膜的拉伸强度显著增强,与PLA膜相比最高增长了32.6%。由于Ag NPs极强的抗菌作用,仅添加少量MMT-Ag NPs的复合抗菌膜就对大肠杆菌和金黄色葡萄球菌表现出了优异的抗菌作用,抑菌率均达到了95%以上。

Silvernanoparticles(Ag NPs) loaded montmorillonite composite antibacterial particles(MMTAgNPs) were synthesized using polydopamine(PDA) as a secondary reaction platform. Composite antibacterial film(PLA/PDA/MMT-AgNPs) was prepared by mixing polylactic acid(PLA) and MMTAgNPs by solvent evaporation method. The composition, phase structure, microstructure and thermal stability of MMT-AgNPs were characterized by FTIR, XRD, TEM and TGA.The microstructure, physical properties and antimicrobial activity of PLA/PDA/MMT-Ag NPs composite antibacterial film were also studied. The results showed that PDA modified MMT still retained its original phase structure, and silver nanoparticles were successfully loaded on the surface of MMT with a loading of 12.2%. The tensile strength of PLA/PDA/MMT-Ag NPs composite antibacterial film was significantly increased, with a maximum increase of 32.6% compared with that of PLA film. Due to extremely strong antibacterial effect of AgNPs, the composite antimicrobial film with very low content of MMT-AgNPs exhibited remarkably antimicrobial activities against E. coli and S. aureus, and both bacteriostasis rates were over 95%.