《伤寒论》经方小柴胡汤加减治疗亚健康病症的研究

Modified Xiaochaihu Decoction in Treatise on Febrile Diseases on Sub-health Symptoms

目的:探究《伤寒论》经方小柴胡汤用于亚健康病证的治疗效果。方法:选取2017年8月—2018年6月来就诊的亚健康病证患者260例,根据随机数字表法将其分为对照组及观察组,每组各130例患者。对照组患者采用常规治疗,观察组患者运用《伤寒论》经方小柴胡汤进行治疗。对比分析两组患者治疗前后睡眠质量、疲劳状态、中医亚健康症状评分;对比治疗后两组亚健康量表各因子评分变化情况。结果:治疗后,两组患者睡眠质量、疲劳状态均优于治疗前,且观察组患者睡眠质量评分(156.02±15.34)、疲劳状态评分(65.10±12.72)明显低于对照组睡眠质量评分(200.79±16.46)、疲劳状态评分(80.89±14.15),差异有统计学意义(P<0.05);观察组患者精神不振、失眠多梦、胸闷气短、倦怠乏力、头晕头重、自汗多汗、食欲不振、心烦易怒等症状评分明显低于对照组,差异有统计学意义(P<0.05)。观察组患者疲劳、躯体不适、负性情绪因子评分明显低于对照组,而睡眠、小便、消化功能、正性情绪、能力及社会关系因子则明显高于对照组,差异有统计学意义(P<0.05)。结论:《伤寒论》经方小柴胡汤用于治疗亚健康病症的效果显著,提高患者睡眠质量,缓解疲劳状态,改善亚健康症状,临床意义重大。

Objective:To explore the effect of Modified Xiaochaihu Decoction on Treatise on Febrile Diseases on sub-health symptoms.Methods:Totally 260 patients with subhealth syndrome from August 2017 to June 2018 were selected and divided into the control group and the observation group according to the random digital table,with 130 patients in each group.The control group was treated with conventional treatment and the observation group were treated with"typhoid fever"by Modified Xiaochaihu Decoction.The quality of sleep,the state of fatigue and the symptom of sub-health of traditional Chinese medicine were compared and analyzed in two groups before and after treatment,and the scores changes of each factor in two sub-health scales after treatment were compared.Results:After treatment,the sleep quality and fatigue state of two groups were all better than those before treatment,and the sleep quality(156.02±15.34)and fatigue state(65.10±12.72)in the observation group were significantly lower than the control group’s sleep quality(200.79±16.46)and the fatigue state(80.89±14.15),and the difference was statistically significant(P<0.05).The scores of the symptoms in the observation group were significantly lower than those in the control group(P<0.05).The scores of fatigue,somatic discomfort and negative emotional factors in the observation group were significantly lower than those of the control group,while sleep,urine,digestive function,positive emotion,ability and social relations were significantly higher than those in the control group(P<0.05).Conclusion:The effect of Modified Xiaochaihu Decoction in Treatise on Febrile Diseases on sub-health symptoms is significant and has great significance to improve the quality of sleep,relieve fatigue and improve the symptoms of sub-health.