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老年重症肺炎患者肌钙蛋白I的活性及临床意义 被引量:7

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摘要 目的探讨老年重症肺炎患者肌钙蛋白I的活性及临床意义。方法回顾性选择湖州市中心医院老年重症肺炎患者70例作为重症肺炎组、老年普通肺炎患者70例作为普通肺炎组、老年健康体检者70例作为对照组。采用全自动生化分析仪酶动力学法测定肌酸激酶(CK)、肌酸激酶同工酶(CK-MB),采用全自动生化分析仪点发光免疫法测定肌钙蛋白I活性。结果重症肺炎组肌钙蛋白I活性、CK、CK-MB水平均明显高于对照组和普通肺炎组(P<0. 05),对照组和普通肺炎组肌钙蛋白I活性、CK、CK-MB比较差异无统计学意义(P>0. 05)。重症肺炎组治疗后肌钙蛋白I活性、CK、CK-MB水平均较治疗前显著降低(P<0. 05)。重症肺炎死亡患者肌钙蛋白I活性、CK、CK-MB水平显著高于存活者(P<0. 05)。重症肺炎组肌钙蛋白I活性与CK、CK-MB水平均呈正相关(P<0. 05)。结论老年重症肺炎患者肌钙蛋白I活性升高,可作为重症肺炎心肌损害的早期诊断标志物,在评估治疗效果和预后中具有重要意义。
出处 《中国老年学杂志》 CAS 北大核心 2019年第4期828-830,共3页 Chinese Journal of Gerontology
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