壮医穴膏摩及贴敷防治小儿反复呼吸道感染随机对照研究

A Randomized Controlled Study on the Prevention and Treatment of Recurrent Respiratory Tract Infections in Children

目的探讨壮医膏摩及穴贴敷防治小儿反复呼吸道感染(RRTI)的效果。方法将92例(脱落10例)反复呼吸道感染(肺脾气虚证)患儿按随机数表法分为研究组和对照组。研究组以止汗固表膏膏摩及贴敷壮医穴,对照组以同样处方药物汤剂口服,2组药物总剂量相等,其他治疗、护理措施均相同,疗程为60d,观察期为1年,观察指标为年发病次数、平均病程、免疫球蛋白(Ig A、Ig G、Ig M)水平及用药的安全性,研究方法采用随机对照对比治疗前后组内、组间的差异。结果 2组患儿治疗后年发病次数、平均病程均比治疗前显著减少(P <0.05),研究组治疗后年发病次数及病程减少优于对照组;2组患儿治疗后Ig A、Ig G水平均比治疗前显著增高(P <0.05),而且研究组优于对照组,Ig M变化无统计学意义;2组均无不良反应。结论止汗固表膏摩及壮医穴贴敷可提高RRTI患儿的免疫力,对降低其年发病次数、缩短病程具有较好疗效。

Objective To explore the effect of Zhuang medicine cream and acupoint sticking on preventing and treating recurrent respiratory tract infection(RRTI) in children. Methods 92 cases(10 cases drop out) of recurrent respiratory infection(as lung and spleen-qi deficiency syndrome) were divided into experimental group and control group according to the random number table method. The experimental group was treated with Zhuang medicine cream and acupoint sticking, and the control group was taken orally with the same prescription drugs, the total dosage of the 2 groups was equal, the other treatment and nursing measures were the same, the course of treatment was 60 days, the observation period last 1 year, the observation index was the number of annual incidence, the average course of disease, the level of immunoglobulin(IgA, IgG, IgM) and the safety of drug use. Results The number of annual incidence and the average course of disease after treatment in the 2 groups were significantly lower than before(P <0.05). The levels of IgA and IgG in the 2 groups were significantly higher than those before the treatment(P <0.05), and the experimental group was better than the control group, and the changes of IgM were not statistically significant. No adverse reaction was found in 2 groups. Conclusion The application of antiperspirant retention cream and Zhuang medicine point can improve the immunity of children with RRTI, and has a good effect on reducing the number of annual onset and shortening the course of disease.