摘要
目的:为临床应用大剂量丙种球蛋白序贯治疗儿童心内膜弹力纤维增生症提供参考。方法:收集兰州大学第二医院儿童医院小儿心血管科2015年收治的4例心内膜弹力纤维增生症患儿的临床资料,分析应用大剂量丙种球蛋白序贯治疗的效果。结果:4例患儿中,2例婴儿(<1岁)因就医及时,治疗6个月后临床缓解(其中1例全程治疗1年后治愈),1例幼儿因就医不及时最终死亡,1例儿童因经济原因终止治疗。结论:及时、全程、大剂量的丙种球蛋白序贯治疗可以促进婴儿特发性心内膜弹力纤维增生症的治愈。
Objective: To provide reference for the clinical application of sequential therapy with high-dose gamma globulin on children with endomyocardial fibroelastosis. Methods: Clinical data of 4 cases of endomyocardial fibroelastosis admitted into the department of pediatric cardiology in the Second Hospital of Lanzhou University in 2015 were collected. Effects of sequential therapy with high-dose gamma globulin on children with endomyocardial fibroelastosis were analyzed. Results: Among the 4 cases, 2 infants (<1 year old) were in clinical remission after 6 months of timely treatment (1 case was cured after 1 year of full treatment), 1 infant died due to delayed treatment, and 1 child was terminated for economic reasons. Conclusion: Timely, full-course, high-dose gamma globulin of sequential therapy can promote the cure of infantile idiopathic endomyocardial fibroelastosis.
作者
杨轶男
董湘玉
刘亚红
牛少敏
王晋
闵丽
Yang Yinan;Dong Xiangyu;Liu Yahong;Niu Shaomin;Wang Jin;Min Li(The Second Hospital of Lanzhou University,Gansu Lanzhou 730030,China)
出处
《儿科药学杂志》
CAS
2019年第3期10-13,共4页
Journal of Pediatric Pharmacy
基金
甘肃省自然科学基金
编号18JR3RA323