左归饮加减对眩晕肾精不足证患者临床疗效及生活质量的影响

The Influence of Modified Left Metal Decoction on Clinical Efficacy and Life Quality of Patients with Vertigo with Kidney Essence Deficiency Syndrome

目的:观察左归饮加减对眩晕肾精不足证患者临床疗效及生活质量的影响。方法:将本院2013年8月至2018年3月收治的眩晕肾精不足证患者70例随机分为对照组和观察组各35例,对照组给予常规西药治疗,观察组在常规西药治疗基础上采用左归饮加减治疗,观察两组患者眩晕症状、临床疗效及生活质量改善情况。结果:观察组治疗后眩晕持续时间显著短于对照组(P <0. 05),基底动脉(arteriae basilaris,BA)、椎基底动脉(vertebrobasilar artery,VA)、大脑后动脉(posterior cerebrl arteriae,PCA)水平均高于对照组(t=7. 091、2. 657、2. 408、2. 531,P <0. 05);观察组有效率为94. 29%,高于对照组的74. 29%(P <0. 05);观察组不良反应发生率为8. 57%,显著低于对照组的20. 00%(χ2=5. 285、4. 200,P <0. 05);观察组治疗后SF-36量表各项内容评分均显著高于对照组(P <0. 05)。结论:左归饮加减可显著改善眩晕肾精不足证患者眩晕症状,提高其生活质量。

Objective:To observe the influence of Modified Left Metal Decoction on clinical Efficacy and life quality of patients with vertigo with kidney essence deficiency syndrome.Methods:Seventy patients with vertigo with kidney essence deficiency syndrome admitted to our hospital from August 2013 to March 2018 were randomly divided into the control group and the observation group,with 35 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with Left Metal Decoction on the basis of conventional Western medicine.The vertigo symptoms,clinical efficacy and quality of life of the two groups were observed.Results:After the treatment,the duration of vertigo in the observation group was significantly shorter than that in the control group(P<0.05),and the levels of basilar artery(BA),vertebrobasilar artery(VA),posterior cerebral artery(PCA)in the observation group were higher than those in the control group(t=7.091,2.657,2.408,2.531,P<0.05).The effective rate in the observation group was 94.29%,which was higher than that in the control group(74.29%,P<0.05).The incidence of adverse reactions in the observation group was 8.57%,which was significantly lower than that in the control group(χ^2=5.285,4.200,P<0.05).After the treatment,the scores of SF-36 scale in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:Modified Left Metal Decoction can significantly improve the vertigo symptoms of patients with kidney essence deficiency syndrome,and improve their quality of life.