肥胖与缺血性卒中

Obesity and ischemic stroke

缺血性卒中是中国人口死亡的主要原因。在缺血性卒中的众多危险因素中,肥胖作为可控因素之一,可通过引起高脂血症、高血压、糖尿病等疾病,间接增高卒中风险。然而,目前关于肥胖对卒中发病、治疗和转归等方面影响的研究结果尚不一致。文章就肥胖与缺血性卒中发病风险、发病机制、转归的关系以及肥胖悖论等进行了综述。

Ischemic stroke is the main cause of death in Chinese population. Among the many risk factors for ischemic stroke, obesity is one of the controllable factors, which can indirectly increase the risk of stroke by causing diseases such as hyperlipidemia, hypertension, and diabetes. However, the current research results on the effects of obesity on the onset, treatment and outcome of stroke are still inconsistent. This article reviews the relationship between obesity and the risks, pathogeneses, outcomes of ischemic stroke, as well as obesity paradox.