应用右美托咪定滴鼻在婴幼儿泪道探通术中的镇静作用

Sedation effect of application of intranasal dexmedetomidine in lacrimal passage probing of infants

目的观察右美托咪定滴鼻镇静应用于婴幼儿泪道探通术的效果。方法泪道探通术患儿40例(47眼),随机分为两组:右美托咪定组为A组,20例(23眼),对照组为B组,20例(24眼)。A组入手术室前30 min经鼻滴入右美托咪定2μg/kg;B组患儿入手术室前不做处理。两组患儿入室后应用0.4%盐酸奥布卡因表面麻醉行泪道探通术。对患儿入室后进行评分。结果 A组患儿在入手术室后镇静评分、情绪状态,与父母分离状态及对手术操作的接受程度均优于B组(P <0.05);手术并发症B组有9例,A组有2例(P<0.05)。结论应用右美托咪定滴鼻镇静可提高患儿泪道探通术中配合度,减少手术并发症。

Objective To observe the sedation efficacy of application of intranasal dexmedetomidine in lacrimal passage probing of infants. Methods Forty-seven eyes of 40 infants received lacrimal passage probing. All cases were randomly divided into 2 groups. Group A ,23 eyes of 20 cases, recieved application of dexmedetomidine intranasally with a dose of 2 μg/kg at 30 min before entering the operating room. Group B ,24 eyes of 20 cases, did not receive any treatment. All patients in the two groups treated with lacrimal passage probing after anaesthesia with 0. 4% oxybuprocaine hydrochloride. The various states of infants after entering the operating room were graded. Results Group A was significantly better than those of group B at the sedation score, emotion state, parental separation and acceptance of surgical operation ( P < 0. 05 ). The complications occurred in group B in 7 cases and 2 cases in group A( P < 0. 05). Conclusion Application of intranasal dexmedetomidine in lacrimal passage probing can improve surgical coordination of infant and reduce children' s surgical complications.