子宫内膜脱落细胞检查在子宫内膜癌筛查中的应用

Application of Exfoliated Endometrial Cells in Screening Endometrial Cancer

目前对子宫内膜癌的诊断是以组织学病理结果为"金标准",但是获取标本的检查大多是有创的,给患者的身心带来一定的痛苦。基于子宫内膜脱落细胞的细胞学病理以及基因测序技术,以其无痛性、准确性、易操作以及低成本的优势为内膜疾病诊断提供了新的契机,被医生和患者所接受。然而目前还未形成统一的诊断标准,未来需要更多的临床实验来发现和解决存在的问题。本文对子宫内膜脱落细胞检查在子宫内膜疾病诊断中的应用发展及现况进行综述。

The diagnosis of endometrial cancer is based on histopathological results as the “gold standard” by now, but the process of obtaining the samples is invasive and brings pain to patients physically and spiritually. Cell pathology and gene sequencing based on exfoliated endometrial cells provide a new opportunity for the diagnosis of endometrial diseases with its painless process, accuracy, easy operation and low cost, and are accepted by doctors and patients. However there is no uniform diagnostic criteria, more clinical trials for discovering and solving problems are needed in the future. In this paper, development and application of exfoliated endometrial cells in the diagnosis of endometrial diseases are reviewed.