垂体后叶素联合酚妥拉明治疗支气管扩张所致咯血的效果评价

Effect of pituitrin combined with phentolamine for hemoptysis caused by bronchiectasis

目的:观察用垂体后叶素联合酚妥拉明治疗支气管扩张所致咯血的临床效果。方法:选取成都市双流区第一人民医院在2017年2月至12月期间收治的100例支气管扩张所致咯血患者作为此次研究的对象。根据治疗方式的不同将其分为研究组与对照组(50例/组)。为对照组患者单用垂体后叶素进行治疗,为研究组患者联用垂体后叶素和酚妥拉明进行治疗。然后比较两组患者的临床疗效、咯血症状消失的时间及不良反应的发生情况。结果:研究组患者治疗的总有效率(98%)高于对照组患者治疗的总有效率(78%),P <0.05。治疗后,研究组患者咯血症状消失的时间〔(2.93±1.32)d〕短于对照组患者咯血症状消失的时间〔(4.56±2.12)d〕,P <0.05。在治疗期间,研究组患者不良反应的发生率(4%)低于对照组患者不良反应的发生率(30%),P<0.05。结论:用垂体后叶素联合酚妥拉明治疗支气管扩张所致咯血的临床效果显著,可有效地降低患者不良反应的发生率,促进其康复。

Objective: To observe the clinical effect of pituitrin combined with phentolamine in the treatment of hemoptysis caused by bronchiectasis. Methods: 100 cases of hemoptysis caused by bronchiectasis admitted to chengdu shuangliu district first people * s hospital from February to December 2017 were selected as the subjects of this study. The patients were divided into study group and control group (50 cases/group) according to different treatment methods. Patients in the control group were treated with pituitrin alone, while patients in the study group were treated with pituitrin and phentolamine. Then, the clinical efficacy, disappearance time of hemoptysis and occurrence of adverse reactions were compared between the two groups. Results: the total effective rate of treatment in study group (98%) was higher than that in control group (78%), P < 0.05. After treatment, the disappearance time of hemoptysis in the study group (2.93±1.32) d was shorter than that in the control group (4.56±2.12) d, P < 0.05. During the treatment period, the incidence of adverse reactions in the study group (4%) was lower than that in the control group (30%), P < 0.05. Conclusion: pituitrin combined with phentolamine in the treatment of hemoptysis caused by bronchiectasis has a significant clinical effect, which can effectively reduce the incidence of adverse reactions in patients and promote their recovery.