小蓟饮子加减方治疗良性前列腺增生双极汽化电切术后出血的临床效果

Clinical effect of addition and subtraction of Xiaojiyinzi prescription in the treatment of bleeding after bipolar vaporization of prostate for benign prostatic hyperplasia

目的探讨小蓟饮子加减方治疗良性前列腺增生双极汽化电切术后出血的临床效果。方法选取2013年6月至2017年6月温岭市中医院收治的实施双极汽化电切术良性前列腺增生患者90例为研究对象,将患者按照随机数字表法分成中药观察组和对照组,每组45例。观察组在术后选用小蓟饮子加减方进行治疗,对照组采用口服非那雄胺进行治疗,比较分析两组患者的临床治疗效果。结果术后3 d、术后5 d、术后7 d对照组出血量分别为(13.69±1.27)mL、(8.37±1.23)mL、(6.13±0.58)mL,观察组分别为(9.22±1.18)mL、(6.12±0.98)mL、(3.98±0.33)mL,两组差异均有统计学意义(t=17.297、P=0.000;t=9.597、P=0.000;t=21.613、P=0.000),两组出血量均随着时间的延长呈下降趋势,且组内每2个时刻比较差异均有统计学意义(均P<0.05);治疗后对照组国防前列腺症状(I-PSS)、慢性前列腺炎症状(NIH-CPSI)评分分别为(13.22±2.95)分、(13.64±4.22)分,观察组分别为(8.11±1.35)分、(7.88±3.06)分,均低于治疗前(t=12.286、P=0.000;t=14.359、P=0.000;t=21.041、P=0.000;t=25.989、P=0.000),且治疗后观察组评分较低,两组间对比差异均有统计学意义(t=8.217、P=0.000;t=7.413、P=0.000)。结论老年男性经尿道前列腺电切术中,出血是最常见的并发症,严重干扰术后的恢复,采用中药小蓟饮子加减治疗可以减少出血量,从而改善术后恢复情况。

Objective To explore the effect of addition and subtraction of Xiaojiyinzi prescription in the treatment of bleeding after bipolar vaporization of prostate for benign prostatic hyperplasia.MethodsFrom June 2013 to June 2017,90 patients with benign prostatic hyperplasia who underwent bipolar electrovaporization in the Traditional Chinese Medicine Hospital of Wenling were selected in this study.The patients were divided into observation group and control group according to a random number table,with 45 cases in each group.The observation group was given addition and subtraction of Xiaojiyinzi prescription,while the control group was treated with finasteride orally.The clinical effects of the two groups were compared and analyzed.ResultsThe amount of bleeding in the control group at 3 days,5 days and 7 days after operation were(13.69±1.27)mL,(8.37±1.23)mL,(6.13±0.58)mL,respectively,which in the observation group were(9.22±1.18)mL,(6.12±0.98)mL,(3.98±0.33)mL,respectively,there were statistically significant differences between the two groups(t=17.297,P=0.000,t=9.597,P=0.000,t=21.613,P=0.000).The amount of bleeding in both two groups decreased with the prolongation of time,and the differences were statistically significant between each two moments(all P<0.05).After treatment,the I-PSS and NIH-CPSI scores in the control group were(13.22±2.95)points and(13.64±4.22)points,respectively,which in the observation group were(8.11±1.35)points and(7.88±3.06)points,respectively,which were lower than those before treatment,and the differences were statistically significant(t=12.286,P=0.000,t=14.359,P=0.000,t=21.041,P=0.000,t=25.989,P=0.000).The scores in the observation group after treatment were lower than those in the control group,and the differences were statistically significant between the two groups(t=8.217,P=0.000,t=7.413,P=0.000).ConclusionHemorrhage is the most common complication of transurethral resection of prostate in elderly men,which seriously interferes with postoperative recovery.The addition and subtraction of Xiaojiyinzi prescription can reduce bleeding and improve postoperative recovery.