老年舌咽神经痛患者接受显微外科手术治疗的临床研究

Clinical study of microsurgery treatment for glossopharyngeal neuralgia in aged patients

目的本研究是通过调查老年舌咽神经痛患者接受显微外科手术治疗的近期和远期随访结果,以分析其疗效和安全性。方法回顾性分析同一治疗组经显微外科手术治疗的55例舌咽神经痛患者资料,将65岁以上的25例老年患者设为观察组,65岁以下的30例患者为对照组。分析两组患者的临床特点、术后并发症及短期疗效和长期预后的差异。结果(1)观察组患者平均年龄(71.88±5.95)岁,对照组(52.57±5.88)岁(t=12.052,P<0.001)。(2)观察组合并各种基础疾病的概率(56.0%),对照组(13.3%)(χ^2=9.421,P=0.001)。(3)两组患者术后平均住院时间差异无统计学意义(t=0.268,P=0.551)。(4)术后3d内总并发症比较差异无统计学意义(χ^2=0.068,P=0.562)。(5)两组患者1个月、3个月、6个月、1年近远期预后差异无统计学意义(均P>0.05)。结论老年舌咽神经痛患者的临床特征、接受手术治疗的预后以及手术风险均与非老年患者相当,老年舌咽神经痛患者接受显微外科手术是安全、有效的,值得临床推广。

Objective To investigate the safety and efficacy of microsurgery for glossopharyngeal neuralgia in aged patients by analyzing short-term and long-term follow-up outcomes. Methods Clinical data of 55 glossopharyngeal neuralgia patients treated with microsurgery were retrospectively analyzed.Among them, 25 patients aged over 65 years were assigned into the observation group, and 30 patients under 65 years were assigned into the control group.Clinical characteristics, postoperative complications, short-term efficacy and long-term prognosis were compared between the two groups. Results There was a significant difference in the average age between the observation group and the control group〔(71.88±5.95)years vs.(52.57±5.88)years,(t=12.052, P<0.001)〕. The incidence of concomitant diseases was higher in the observation group than in the control group(56.0%vs.13.3%,χ^2=9.421, P=0.001). No significant difference was found in length of hospital stay or postoperative complications between the two groups(t=0.268, P=0.551;χ^2=0.068, P=0.562). There was no significant difference in short- and long-term prognosis at 1, 3, 6 months and 1 year after microsurgery(P>0.05). Conclusions Clinical characteristics, prognosis after microsurgery and surgery risks in aged glossopharyngeal neuralgia patients are comparable to those in younger glossopharyngeal neuralgia patients.Therefore, microsurgery is safe and effective in treating glossopharyngeal neuralgia in aged patients and should be encouraged in clinical practice.