胃结直肠癌术后腹腔感染性并发症的现状研究(PACAGE研究)

Prediction of abdominal complication after gastroentero-logical surgery for gastric and colorectal cancer

长期以来,胃癌和结直肠癌术后并发症的发生严重影响患者康复,乃至患者生命安全。据中国胃肠肿瘤外科联盟的统计数据,腹腔感染性并发症是导致二次手术和术后死亡的主要原因,值得临床医师关注。然而,胃癌和结直肠癌术后腹腔感染的发生率各医疗中心报道差异巨大。由于缺乏来自全国范围的数据,目前仍无法合理预计腹腔感染性并发症的发生率并制订相应的循证诊断与治疗策略。胃结直肠癌术后腹腔感染性并发症发生现状的研究旨在全国范围内通过多中心前瞻性队列研究调查我国胃结直肠癌术后腹腔感染的发生率、分类及转归情况,并在全国范围内推广并发症的规范化登记,为进一步提高手术安全性、预防腹腔感染发生、降低术后并发症提供依据。

The postoperative complications in patients with gastric or colorectal cancer has been common but seriously affecting patients′ recovery and even their life safety. According to the database of China Gastrointestinal Cancer Surgery Union, abdominal infectious complications are the main causes of secondary surgery and postoperative death, which deserve clinical attention. However, the incidence rate of postoperative abdominal infection varies widely from center to center. Due to the lack of nationwide data, it is unable to determine the incidence of abdominal infectious complications reasonably and formulate the corresponding strategies of evidence-based diagnosis and treatment. Therefore, this multi-center prospective cohort study, i. e. prediction of abdominal complication after gastroenterological surgery (PACAGE), aims to investigate the incidence, classification and outcomes of postoperative abdominal infection in patients with gastric or colorectal cancer, to implement the standardization of the complication registration, and to provide necessary data for improving surgical safety, preventing abdominal infection and decreasing the rate of postoperative complications in the future.