电话随访对维族哈族首发精神分裂症患者服药依从性及复发的影响

Effect of telephone follow-up on medication compliance and recurrence in first-episode schizophrenia patients of Uighur and Kazakh

目的探讨电话随访对维吾尔族(维族)和哈萨克族(哈族)首发精神分裂症患者服药依从性及复发的影响.方法将病情稳定≥3个月,出院后达到临床症状缓解或消失标准的80例维族和哈族首发精神分裂症患者按随机分配原则分为随访组和对照组,每组40例,随访组出院后在常规出院指导基础上给予电话随访,对照组仅给予常规出院指导、自行门诊随诊.于出院时及随访1a后采用阳性与阴性症状量表评定精神症状,采用服药及复诊依从性评分法评定服药及复诊依从性,统计复发率.结果出院时两组阳性与阴性症状量表、服药及复诊依从性评分比较差异无统计学意义(P>0.05);随访1a随访组仅阳性与阴性症状量表评分较出院时显著升高(P<0.01),对照组阳性与阴性症状量表、服药及复诊依从性评分均较出院时显著升高(P<0.01),随访组阳性与阴性症状量表、服药及复诊依从性评分显著低于对照组(P<0.01);随访组复发率(25.0%)显著低于对照组(47.5%)(P<0.05).结论电话随访可以提高维族和哈族首发精神分裂症患者服药依从性及复诊依从性,降低临床复发风险,适合在临床随访中应用.

Objective To investigate the effect of telephone follow-up on medication compliance and recurrence in first-episode schizophrenia patients of Uighur and Kazakh.Methods 80 patients of Uighur and Kazakh with first-episode schizophrenia who had stable disease>3 months and reached the standard of clinical symptom relief or disappearance after discharge were divided into follow-up group and controlgroup according to the principle of random distribution,40 cases in each group.The follow-up group was followed by telephone follow-up on the basis of conventional discharge guidance,the control group was only given routine discharge guidance and voluntary outpatient clinic.At the time of discharge and after1 year of follow-up,the mental symptom was assessed by PANSS.The medication and follow-up compliance scale was used to assess medication compliance and follow-up compliance,and the recurrence rate was calculated.Results There was no significant difference in the PANSS score,medication and follow-up compliance score between the two groups at discharge(P>0.05).After one year of follow-up,the PAN-SS score in the follow-up group was significantly higher than that at discharged(P<0.01),the PANSS scale,medication and follow-up compliance scores of the control group were significantly higher than those at the time of discharge(P<0.01).The PANSS scale,medication and follow-up compliance scores of the follow-up group were significantly lower than those of the control group(P<0.01).The recurrence rate of the follow-up group(25.0%)was significantly lower than that of the control group(47.5%)(P<0.05).Conclusion Telephone follow-up can improve compliance in patients with first-episode schizophrenia of Uyghur and Kazak,and reduce the risk of clinical recurrence.It is suitable for clinical follow-up applications.