血清癌胚抗原、甲胎蛋白、糖链抗原-125和糖链抗原19-9联合检测对卵巢恶性肿瘤的诊断价值研究

Diagnostic value of combined use of serum carcinoembryonic antigen, alpha-fetoprotein, carbohydrate antigen 125 and carbohydrate antigen in malignant ovarian tumors

目的研究血清中癌胚抗原(CEA)、甲胎蛋白(AFP)、糖链抗原-125(CA125)和糖链抗原(CA19-9)含量对卵巢恶性肿瘤的诊断意义。方法抽取本院妇产科2010年5月-2014年6月收治卵巢肿瘤患者138例为研究组,抽取相同时间来院体检健康女性120例为对照组。统计血清中CEA、AFP、CA125以及CA19-9含量。结果研究组患者血清中CEA、AFP、CA125以及CA19-9含量显著高于对照组(P<0.05)。恶性肿瘤患者血清CEA、AFP、CA125以及CA19-9含量显著高于良性肿瘤患者(P<0.05)。结论卵巢恶性肿瘤患者血清CEA、AFP、CA125和CA19-9含量显著升高。

Objective To investigate the diagnostic values of serum carcinoembryonic antigen(CEA), alpha-fetoprotein(AFP), carbohydrate antigen 125(CA125) and carbohydrate antigen(CA19-9) in malignant ovarian tumors. Methods A total of 138 ovarian tumors patients were collected during May 2010-June 2014 in our hospital, and 120 healthy women were included as the control group. The serum levels of CEA, AFP, CA125 and CA19-9 were analyzed. Results It showed that the serum levels of CEA, AFP, CA125 and CA19-9 in patients with ovarian tumors were significantly higher than those in the healthy controls(P<0.05). Moreover, the levels of serum CEA, AFP, CA125 and CA19-9 in patients with malignant ovarian tumors were significantly higher than those in patients with benign ovarian tumors(P<0.05). Conclusion Serum CEA, AFP, CA125 and CA19-9 levels in patients with ovarian malignant tumors significantly increased.