降钙素原、超敏C反应蛋白、白细胞检测在诊断老年细菌性肺炎中的应用

Application of procalcitonin, high-sensitivity C-reactive protein and leukocyte detection in diagnosis of senile bacterial pneumonia

目的:探究降钙素原(PCT)、超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)检测在诊断老年细菌性肺炎中的应用.方法:选取2016年3月~2017年3月收治的60例老年细菌性肺炎患者临床资料进行分析,将其设为研究组,并取60例同期体检健康者作为对照组,均采集血标本行PCT、hs-CRP、WBC检测,比较两组检测情况.结果:研究组PCT(5.71±3.23)ng/mL、hs-CRP(49.45±37.55)mg/L、WBC(13.32±8.19)×10^9/L均显著高于对照组(P<0.05);研究组3-4级患者检出PCT(7.69±2.62)ng/mL、hs-CRP(55.32±18.66)mg/L、WBC(17.04±3.13)×10^9/L显著高于1、2级(P<0.05).结论:老年细菌性肺炎可应用PCT、hs-CRP、WBC等指标进行诊断,三者联合检验准确率更高,且可对患者严重程度进行评估,可指导临床治疗方案的制定.

Objective: To investigate the application of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP) and white blood cell count (WBC) in the diagnosis of senile bacterial pneumonia. Methods: The clinical data of 60 elderly patients with bacterial pneumonia admitted from March 2016 to March 2017 were analyzed, which was used as the study group, and 60 healthy subjects were taken as the control group. All blood samples were collected for PCT, hs-CRP and WBC detection, and the two groups were compared. Results: The PCT (5.71 ±3.23) ng/mL, hs-CRP (49.45±37.55) mg/L, and WBC (13.32±8.19)×10^9/L were significantly higher in the study group than in the control group (P<0.05). PCT (7.69±2.62) ng/mL, hs-CRP (55.32+18.66) mg/L, WBC (17.04±3.13)×10^9/L in grade 3 -4 patients were significantly higher than grade l and grade 2 (P<0.05). Con elusion: The elderly patients with bacterial pneumonia can be diagnosed by using PCT, hs-CRP, WBC and other indicators. The combined accuracy of the three tests is higher, and the severity of the patients can be evaluated, which can guide the formulation of clinical treatment plans.