孕早期体力活动对产后抑郁症状的影响

Effects of physical activity during early pregnancy on postpartum depressive symptoms

目的探究孕早期体力活动与产后抑郁症状的关系。方法对2 580名女性进行前瞻性研究,探究妊娠早期(0～16周)体力活动与产后6周的抑郁症状之间的关系。体力活动通过社会支持调查工具评估,产后6周抑郁症状通过爱丁堡产后抑郁量表评估。本研究中,产后抑郁症状筛选阳性约为11. 4%(筛选阳性临界值为9/10分)。在统计分析过程中,分别使用连续变量(将总分log转换)和分类变量(将总分四等分组)进行分析。采用Logistic回归模型分析体力活动与产后抑郁症状之间的关系。结果相对于低体力活动量组,中等体力活动量组产后抑郁症状的发生风险有降低的趋势(OR=0. 74,95%CI:0. 57～0. 95; a OR=0. 77,95%CI:0. 59～1. 01)。相对于低体力活动量组,高体力活动量组产后抑郁症状的发生风险有增加的趋势(OR=1. 35,95%CI:0. 51～3. 55; a OR=1. 24,95%CI:0. 45～3. 40)。结论孕早期体力活动与产后抑郁症状之间的关联性可能因活动量的大小而方向不同。

Objective To explore the relationship between physical activity during early pregnancy and postpartum depressive symptoms. Methods We conducted a prospective study of 2 580 women and explored the relationship between physical activity during early pregnancy (0-16 weeks) and postpartum depressive symptoms at 6 weeks. Physical activity was assessed during the first trimester by the social support inventory and postpartum depressive symptoms at 6 weeks were assessed using the Edinburgh postnatal depression scale. The prevalence of postpartum depression symptoms in this study was 11.4%(cutoff: 9/10). In the statistical analysis process, continuous variables (log-converted total scores) and categorical variables (divided the total score into four equal groups) were used for analysis. A logistic regression model was used to analyze the relationship between physical activity and postpartum depressive symptoms. Results Compared with the low physical activity group, the risk of postpartum depressive symptoms decreased in the moderate physical activity group ( OR =0.74, 95% CI : 0.57-0.95;a OR =0.77, 95% CI : 0.59-1.01). Compared with the low physical activity group, the risk of postpartum depressive symptoms increased in the high physical activity group ( OR =1.35, 95% CI : 0.51-3.55;a OR =1.24, 95% CI : 0.45-3.40). Conclusion The association between physical activity during early pregnancy and postpartum depressive symptoms may vary with the magnitude of the activity.