柔肝通络汤治疗脑梗死急性期40例临床观察

Clinical effect of Rougan Tongluo decoction in treatment of acute - stage cerebral infarction: An analysis of 40 cases

目的:观察柔肝通络汤治疗脑梗死急性期(阴虚络瘀证)的临床疗效。方法:将脑梗死急性期(阴虚络瘀证)患者80例,随机分为2组,每组各40例。治疗组采用柔肝通络汤治疗,对照组采用西医常规治疗。结果:综合疗效总有效率治疗组为87. 5%,对照组为72. 5%,组间比较,差异有统计学意义(P <0. 05);中医证候疗效总有效率治疗组为90. 0%,对照组为75. 0%,组间比较,差异有统计学意义(P <0. 05);2组血液流变学指标、NIHSS评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P <0. 01)。结论:柔肝通络汤治疗脑梗死急性期(阴虚络瘀证)有较好疗效,优于西医常规治疗。

Objective: To investigate the clinical effect of Rougan Tongluo decoction in the treatment of acute - stage cerebral infarction with Yin deficiency and collateral obstruction. Methods: A total of 80 patients in the acute stage of cerebral infarction with Yin deficiency and collateral obstruction were enrolled and randomly divided into treatment group and control group, with 40 patients in each group. The patients in the treatment group were given Rougan Tongluo decoction, and those in the control group were given conventional Western medicine treatment. Results:There were significant differences between the treatment group and the control group in overall response rate(87. 5% vs 72. 5%,P <0. 05 )and overall response rate of TCM syndrome(90. 0% vs 75. 0%,P <0. 05). Both groups had significant changes in hemorheologieal indices and NIH Stroke Scale score after treatment, and there were significant differences in these indices between the two groups after treatment ( P <0. 01). Conclusion : Rougan Tongluo decoction has a better clinical effect than conventional Western medicine treatment in the treatment of acute - stage cerebral infarction with Yin deficiency and collateral obstruction.