摘要
猪带绦虫是重要的人体寄生虫之一,其囊尾蚴和成虫均可致病,其中囊尾蚴所致的囊虫病危害最为严重。近年来,国内、外在细胞和分子水平上对囊虫病免疫发病机制进行了大量研究,初步明确了囊尾蚴入侵和宿主免疫效应及发病间的关系。本文就囊虫病免疫发病机制研究做一综述,旨在为囊虫病的免疫预防和治疗提供新思路。
Taenia solium is one of the most important human parasites and its cysticercus and adult worms are both pathogenic. Cysticercosis caused by cysticercus is the most serious. In recent years, a large number of studies have been conducted on the immunological pathogenesis at cellular and molecular levels in local and abroad. The relation between cysticercus invasiveness and host immune effects and immunological pathogenesis has been preliminarily clarified. This article reviews the immunological pathogenesis of cysticercosis to provide new ideas for the immunoprevention and treatment of this disease.
作者
张悦
刘美辰
周必英
Zhang Yue;Liu Meichen;Zhou Biying(Department of Parasitology, Zunyi Medical University, Zunyi 563000, China)
出处
《中华地方病学杂志》
CAS
CSCD
北大核心
2019年第3期253-258,共6页
Chinese Journal of Endemiology
基金
贵州省优秀青年科技人才基金项目(黔科合平台人才[2017]5629)
贵州省卫计委科研项目(gzwjkj2016-1-048)
省市科技合作专项资金项目(省市科合[2015]52)
贵州省教育厅青年科技人才成长项目(黔教合KY字[2018]225).
关键词
囊虫病
囊尾坳
免疫发病机制
Cysticercosis
Cysticercus
Immunological pathogenesis