摘要
近年来,妇科肿瘤的发病率和死亡率仍在逐年上升,面向肿瘤的靶向免疫治疗研究也与日俱增。文章就妇科肿瘤的免疫治疗现状,主要集中在治疗性疫苗、免疫检查点抑制剂和免疫细胞改造3个方面进行阐述,为妇科肿瘤的临床治疗和基础研究提供依据。
In recent years,the morbidity and mortality of gynecological tumors are constantly increasing,and the researches on targeted immunotherapy for tumors are correspondingly rising. The article reviews the present status of gynecological tumor immunotherapy,mainly in three aspects:therapeutic vaccines,immune checkpoint inhibitors and immune cells transformation,to provide information for clinical treatment and basic research.
作者
杨喆
王轶英
王悦
YANG Zhe;WANG Yi-ying;WANG Yue(People's Hospital of Zhengzhou University,Henan Provincial People's Hospital,Zhengzhou450003,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2019年第3期214-219,共6页
China Cancer
基金
河南省医学科技攻关计划项目(201602190)
关键词
妇科肿瘤
免疫治疗
治疗性疫苗
免疫检查点抑制剂
免疫细胞改造
gynecological tumors
immunotherapy
therapeutic vaccines
immune checkpoint inhibitors
immune cells transformation