负性情绪对结直肠癌患者术后生存质量的影响

Effect of negative emotion on postoperative quality of life in patients with colorectal cancer

目的 调查结直肠癌术后患者抑郁和焦虑情况,分析其对患者生存质量的影响。方法 选取2016年3月至2017年12月于我院行手术治疗的112例结直肠癌患者为研究对象,采用焦虑自评量表(SAS)、汉密尔顿抑郁量表(HAMD)及简明健康调查量表(SF-36)评价患者的负性情绪及生活质量。结果 直肠癌患者手术后SAS平均分为(63. 5±5. 8)分,焦虑发生率为57. 14%(64/112); HAMD平均分为(22. 6±3. 5)分,抑郁发生率为43. 75(49/112); 13例患者同时存在抑郁与焦虑;非焦虑非抑郁患者12例。经统计学处理,四组患者的生活质量各维度评分比较差异有统计学意义(P <0. 05)。采用Pearson线性相关分析结果显示,患者抑郁评分及焦虑评分与生活质量中总体健康、生理功能、生理职能、躯体疼痛、活力、社会功能、情感职能及精神健康均呈负相关(P <0. 05)。结论 结直肠癌术后患者抑郁、焦虑的发生较为普遍,对术后患者的生活质量有显著影响,提示在后期的治疗中应注意心理干预,从而提高其生活质量。

Objective To investigate the depression and anxiety condition of patients with colorectal cancer after surgery,and to analyze its impact on these patients'quality of life.Methods A total of 112 patients with colorectal cancer who underwent surgery from March 2016 to December 2017 in our hospital were selected as the study subjects.We used the self-rating anxiety scale(SAS),Hamilton depression scale(HAMD)and the MOS item short from health survey(SF-36)to evaluate the negative emotion of patients and their quality of life.Results The average SAS score of patients with rectal cancer after surgery was(63.5±5.8),and the incidence of anxiety was 57.14%(64/112).The average score of HAMD was(22.6±3.5),and the incidence of depression was 43.75%(49/112).A total of 13 patients had both depression and anxiety,and 12 patients didn’t have depression and anxiety.The statistical analysis showed that there was statistical difference in the quality of life scores of the four groups of patients(P<0.05).The Pearson linear correlation analysis showed that patients'depression scores and anxiety scores were negatively correlated with general health,physiological function,physiological role,body pain,vitality,social function,emotional function and mental health of the quality of life(P<0.05).Conclusion The incidence of depression and anxiety in patients with colorectal cancer is common,which has a significant effect on the quality of postoperative life of patients.We can pay attention to psychological intervention in the later treatment,thus improving their quality of life.