污水处理厂出水中抗雄激素样化合物控制的优先性研究

Control Priority Order of the Environmental Antiandrogens in Effluents of Wastewater Treatment Plants

污水处理厂出水是环境中内分泌干扰物的重要来源之一。针对关注较少的抗雄激素样内分泌干扰物,在已有研究基础上,依据抗雄激素样化合物的抗雄激素样活性风险,建立了污水处理厂出水中抗雄激素样化合物控制的优先性排序方法。在污水处理厂出水中,共有147种疑似抗雄激素样化合物需要关注,主要为农药类,约占总数的60%。抗雄激素样活性风险排名前10%的化合物如下:邻苯二甲酸二丁酯、邻苯二甲酸二己酯、双酚A、溴螨酯、对叔辛基酚、腐霉利、烯菌酮、氯苯嘧啶醇、烯酰吗啉、杀螟松、十二烷基酚、敌草隆、咯菌酯、2-羟基-4'-甲氧基二苯甲酮、以及邻苯基苯酚。

A major source of endocrine disrupting chemicals( EDCs) into the aquatic environment is the effluents of wastewater treatment plants( WWTPs). In the aquatic ecosystems,much of the EDCs research has concentrated on estrogenic compounds and in this study antiandrogenic compounds were paid attention to. On the basis of antiandrogenic activity risks,the approach to prioritizing antiandrogens in the effluents of WWTPs was constructed. In total,147 antiandrogens had been reported and nearly 60% of which were pesticides. The developed procedure was applied and the first ten percent antiandrogens were as followed,dibutyl phthalate,di-n-hexyl phthalate,bisphenol A,bromopropylate,4-t-octylphenol,procymidone,vinclozolin,fenarimol,dimethomorph,fenitrothion,4-n-dodecylphenol,diuron,fludioxonil,2-hydroxy-4’-methoxybenzophenone,and o-phenylphenol.