脑卒中患者癫痫发作的危险因素及脑电图表现

Multi Factor Analysis and Electroencephalogram of Epileptic Seizures in Stroke Patients

【目的】分析脑卒中后蹶痫发作的危险因素及患者脑电图表现。【方法】选取本院2011年9月至2017年9月收洽的1396名脑卒中患者作为研究对象,最终纳入951名。根据脑卒中后癲痫是否发作,分为娠痫发作组、无癲痫发作组。分析脑卒中后娠痫发作的危险因素.并观察患者脑电图表现。【结果】本次研究脑卒中后癲痫发作发生率为5.68%,其中早发型癫痫占比55.56%,迟发型癲痫占比44.44%。脑卒中后癲痫发作患者脑电图呈弥散性异常占25.93%,局限性异常占48.15%。多因素回归分析显示病灶部位、病灶范围、高同型半胱氨酸血症和NIHSS评分≥25分是脑卒中后癫痫发作的独佥危险因素。【结论】对于病灶部位在皮质、病灶范国大、高同型半胱氨酸血症和NIHSS评分≥25分的脑卒中患者应高度警惕娠痫发作。

【Objective】To analyze the risk factors of post-stroke epilepsy and the electroencephalogram(EEG)of the patients.【Methods】A total of 1,396 stroke patients admitted to our hospital from September 2011 to September 2017 were selected as the study subjects,and 951 stroke patients were included in the study.According to whether epilepsy occurs after stroke,they were divided into epilepsy seizure group and non-epilepsy seizure group.The risk factors of epileptic seizures after stroke were analyzed and the EEG manifestations of the patients were observed.【Results】In this study,the incidence of epileptic seizures after stroke was 5.68%,of which early-onset epilepsy accounted for 55.56%,late-onset epilepsy accounted for 44.44%.Disseminated abnormalities in EEG and localized abnormalities were found in 25.93%and 48.15%of patients with epileptic seizures after stroke.Multivariate regression analysis showed that the location,extent,hyperhomocysteinemia and NIHSS score(≥25)were independent risk factors for epileptic seizures after stroke.【Conclusion】Patients with stroke in the cortex,large extent of lesions,hyperhomocysteinemia,and NIHSS score≥25 should be highly alert to seizures.