胸腔镜下肺叶切除与亚肺叶切除对IA期非小细胞肺癌治疗的效果

Effects of thoracoscopic lobectomy and sublobar resection on stage IA non-small cell lung cancer

目的探讨胸腔镜下肺叶切除术、胸腔镜下亚肺叶切除术对IA期非小细胞肺癌的治疗效果。方法依据随机数字表法将山西大医院2014年2月至2018年2月收治的82例IA期非小细胞肺癌患者分为研究组与对照组,每组41例。研究组予以胸腔镜下亚肺叶切除术治疗,对照组行胸腔镜下肺叶切除术,记录两组IA期非小细胞肺癌患者手术情况、随访情况相关数据。结果研究组术后引流时间、术后3 d视觉模拟评分法(VAS)评分情况以及术后肺部感染、肺不张、左心力衰竭发生率均少低对照组(P<0.05),两组术后住院时间比较差异未见统计学意义(P>0.05),两组随访期间无瘤生存率、死亡率、复发及转移率比较差异统计学意义(P>0.05)。结论胸腔镜下亚肺叶切除术治疗IA期非小细胞肺癌有效,临床医生应根据患者实际情况选择合适的手术方案,确保患者临床治疗效果及预后。

Objective To investigate the effects of thoracoscopic lobectomy and thoracoscopic sublobectomy on IA stage non-small cell lung cancer (NSCLC). Methods Eighty-two patients with stage IA non-small cell lung cancer in Shanxi Dayi Hospital from February 2014 to February 2018 were divided into study group and control group, with 41 cases in each group by random number table method. The patients in the study group were treated with sublobectomy under thoracoscopy and those in the control group were treated with thoracoscopic lobectomy. The results of two groups of patients with IA stage NSCLC were recorded and followed up. Results The postoperative drainage time, postoperative 3 d VAS score, pulmonary infection, atelectasis and left heart failure in the study group were lower than those in the control group (P<0.05). There was no significant difference in postoperative hospital stay between the two groups (P>0.05). There was no significant difference in tumor free survival rate, mortality rate, recurrence or metastasis rate between the two groups (P>0.05). Conclusions Thoracoscopic subpulmonary lobectomy is effective on non-small cell lung cancer (NSCLC) in IA stage. The clinicians should choose the appropriate operation plan according to the actual situation of the patients, so as to ensure the clinical treatment effect and prognosis of the patients.