经纤维支气管镜盐酸氨溴索灌洗治疗小儿重症肺炎的疗效观察

Observation on curative effects of ambroxate hydrochloride by fiberoptic bronchoscopy on severe pneumonia in children

目的探讨经纤维支气管镜盐酸氨溴索灌洗治疗小儿重症肺炎的临床疗效。方法选择2017年5月至2018年5月荆州市妇幼保健院儿科收治的重症肺炎患儿71例,随机分为对照组(35例)与治疗组(36例)。对照组给予抗感染、止咳化痰及呼吸支持等常规治疗,治疗组在对照组的基础上加用纤维支气管镜盐酸氨溴索肺泡灌洗。观察两组治疗前后症状、肺部体征变化及肺部病灶影像学改变,比较两组总有效率。结果治疗组有效率为94.4%,对照组为71.4%,两组比较差异有统计学意义(P<0.05)。结论经纤维支气管镜盐酸氨溴索灌洗治疗小儿重症肺炎,临床疗效佳。

Objective To investigate the clinical effects of ambroxate hydrochloride by fiberoptic bronchoscopy on severe pneumonia in children. Methods Seventy-one patients with severe pneumonia, who were hospitalized in Maternal and Children Health Care Hospital of Jingzhou from May 2017 to May 2018, were selected and divided into control group (35 caes) and treatment group (36 cases). Patients in control group were given routine treatment, and patients in treatment group were given ialveolar lavage of ambroxate by fiberoptic bronchoscope on the basis of treatment for control group. The symptoms, lung signs and lung lesions and radiological data of the two groups before and after treatment were observed. Results The effective rate was 94.4 % in treatment group, and it was 71.4 % in control group, and the difference between the two groups was significant (P<0.05). Conclusions Ambroxol hydrochloride with fiberoptic bronchoscopy is effective in the treatment of severe pneumonia in children.