清肺抑火胶囊治疗风热犯肺型急性支气管炎的临床观察

Clinical observation on Qingfei Yihuo Capsules in treating acute bronchitis with syndrome of wind-heat invading lung

目的:探讨清肺抑火胶囊治疗风热犯肺型急性支气管炎的临床疗效。方法:采用随机分组、平行对照的方法,选取风热犯肺型急性支气管炎患者150例,随机分为治疗组75例和对照组75例。对照组患者给予西医基础治疗,治疗组患者给予西医基础治疗结合清肺抑火胶囊口服,两组疗程均为10 d。评价两组的临床疗效,比较两组患者的咳嗽消失率、咳嗽视觉模拟评分(VAS)、临床症状总积分,观察两组患者的常见临床症状改善情况。结果:治疗后,治疗组和对照组的临床总有效率分别为97.3%和68.0%,治疗组的疗效优于对照组(P<0.01)。治疗后,治疗组的咳嗽消失率为52.0%,对照组为17.3%,治疗组的咳嗽消失率明显高于对照组(P<0.01)。与治疗前相比,治疗组治疗第1天患者的咳嗽VAS评分即降低(P<0.05),治疗第2、3、10天患者的咳嗽VAS评分均显著降低(P<0.01),且治疗组患者的评分低于对照组同期(P<0.05,P<0.01);对照组患者在治疗第10天,其咳嗽VAS评分才较治疗前降低(P<0.05)。治疗后,两组患者的症状总积分较治疗前均显著降低(P<0.05,P<0.01),且治疗组患者的总积分低于对照组(P<0.01)。治疗后,两组患者的临床症状均得到明显改善(P<0.05),且治疗组患者的症状改善情况优于对照组(P<0.05)。结论:清肺抑火胶囊可有效缓解急性支气管炎风热犯肺型患者的临床症状,减轻咳嗽的严重程度,明显提高临床疗效。

Objective: To study the clinical efficacy of Qingfei Yihuo Capsules on acute bronchitis with syndrome of wind-heat invading lung. Methods: A randomized and parallel control trial was performed, and 150 patients of acute bronchitis with syndrome of wind-heat invading lung were selected and randomly divided into the treatment group(75 cases) and the control group(75 cases). The patients in the control group were treated with basic therapy of western medicine, and the patients in the treatment group were treated with Qingfei Yihuo Capsules combined with basic therapy of western medicine, with a course of 10 days. The clinical efficacy of the two groups was evaluated, the rate of cough disappearance, the visual analogue scale(VAS) score of cough and the total score of clinical symptoms were compared, and the improvement on the common clinical symptoms was observed. Results: After treatment, the total clinical effective rates of the treatment group and the control group were 97.3% and 68.0% respectively, and the efficacy of the treatment group was better than that of the control group(P<0.01). After treatment, the rate of cough disappearance in the treatment group was 52.0%, and that in the control group was 17.3%. The rate of cough disappearance in the treatment group was significantly higher than that in the control group( P<0.01). Compared with treatment before,on the first day of treatment,the cough VAS score of the treatment group was reduced( P<0.05);on the second,third and tenth day of treatment,the cough VAS scores of the treatment group were significantly reduced( P<0.01),and the VAS scores of the treatment group were lower those that of the control group at same time( P<0.05,P<0.01);while on the tenth day of treatment,the cough VAS score of the control group was reduced compared with treatment before( P<0.05). After treatment,the total score of clinical symptoms was obviously reduced in both groups( P < 0. 05,P<0.01),and the total score of the treatment group was lower than that of the control group( P<0.01). After treatment,the clinical symptoms were significantly improved in both groups( P<0.05),and the improvement of the symptoms in the treatment group was better than that in the control group( P<0.05).Conclusion: Qingfei Yihuo Capsules can effectively relieve the clinical symptoms of acute bronchitis patients with syndrome of wind-heat invading lung,reduce the severity of cough,and improve the clinical efficacy.