造血干细胞移植治疗儿童髓母细胞瘤现状

Current status of hematopoietic stem cell transplantation in childhood medulloblastoma

髓母细胞瘤是儿童期常见颅内肿瘤之一,低危髓母细胞瘤患儿对手术、放疗等常规治疗反应好,但高危、复发髓母细胞瘤患儿疗效欠佳,造血干细胞移植作为治疗难治血液肿瘤疾病的重要手段,在高危、复发髓母细胞瘤治疗中的应用已有10余年历史,现就目前造血干细胞移植在髓母细胞瘤中的应用现状进行综述。

Medulloblastoma is one of common brain tumor in childhood.Low risk patient has good response to convention therapy, such as operation, radiotherapy, but patients with high risk or recurrent patients get worse effect.Hematopoietic stem cell transplantation is an important therapy for refractory hematological disease and cancer, it has been used in high risk and recurrent medulloblastoma for decades.Now, the currant situation of hematopoietic stem cell transplantation in childhood medulloblastoma were summarized.