老年人潜在不适当用药2019版Beers标准解读

Understanding of 2019 Beers criteria for potentially inappropriate medication use in older adults

美国老年医学会公布的Beers标准是老年人潜在不适当用药列表。跨学科专家组审查了自2015年更新以来发表的证据,确定2019年更新标准,包括增加或删除现有标准,或对其建议、依据、证据等级或推荐强度进行修订。2019版Beers标准中保留了2015版标准的5种类型,但针对具体内容进行了更新,如增加或修改抗血栓药物的标准,对许多药物的评价标准依据给出更详细的释义,某些既往标准中药物因已不在美国使用或较少使用、或因不具有年龄风险特性而从标准中剔除。

The American Geriatrics Society(AGS) Beers criteria for potentially inappropriate medication(PIM) use in older adults is an explicit list of PIM that are typically best avoided by older adults. For the 2019 update, an interdisciplinary expert panel reviewed the evidence published since the last update( 2015) to determine if new criteria should be added or if existing criteria should be removed or undergo changes to their recommendation, rationale, level of evidence, or strength of recommendation. Each of the five types of criteria in the 2015 update was retained in this 2019 update. But updated for specific contents: such as increasing or modifying the standard of antithrombotic drugs, a more detailed interpretation of the criteria for the evaluation of many drugs. And in some previous standards, drugs were excluded from the standard because they were no longer used or used less in the United States, or because they did not have age-risk characteristics.