磁控胶囊胃镜对不同特征体检人群上消化道病变的诊断价值

Clinical value of magnetically controlled capsule gastroscopy for the detection of upper gastrointestinal lesions in asymptomatic individuals with different characteristics

目的探讨磁控胶囊胃镜(MCGE)对不同特征体检人群上消化道病变的诊断价值.方法回顾性分析于我院消化内镜中心行MCGE检查的无症状体检人群168例的临床资料,统计MCGE对上消化道病变的检出情况、受检者耐受度及安全性,比较不同特征体检人群的病变检出率.结果 168例受检者中,男104例,女64例;≤45岁者78例,>45岁者90例;单纯体检者138例,有特殊原因者30例.总体病变异常检出率为44.6%,其中胆汁反流、糜烂性胃炎、胃息肉检出率均>8%,糜烂性食管炎、胃隆起病变、胃溃疡检出率为3%~5%,食管下段岛状橘红黏膜、食管隆起病变、胃黄色素瘤、小肠溃疡及小肠血管畸形检出率均<2%.男性受检者总体异常检出率明显高于女性(51.9%比32.8%,P=0.016),以糜烂性胃炎为主;>45岁受检者总体异常检出率明显高于≤45岁者(54.4%比33.3%,P=0.006),以胃息肉和隆起病变为主;单纯体检组总体异常检出率与特殊原因组比较差异无统计学意义(42.8%比53.3%,P=0.291).所有受检者均无胶囊滞留.结论 MCGE安全可耐受,对男性及>45岁受检者的病变检出率更高,为临床上选择受检者及评估检查结果提供依据.

Objective To investigate the diagnostic ability of magnetically controlled capsule gastroscopy(MCGE) for the detection of upper gastrointestinal (GI) lesions in asymptomatic individuals with different characteristics. Methods Cinical data of 168 asymptomatic subjects who received MCGE examination in digestive endoscopy center of our hospital were retrospectively collected and analyzed. Phe detection status of upper GI lesions, the tolerance and safety of the subjects were statistically analyzed, and the detection rate of lesions among the people with different characteristics were compared. Results In 168 subjects,there were 104 males and 64 females. Seventy-eight cases were W45 years old and 90 cases were > 45 years old. There were 138 cases of simple physical examination and 30 cases with special reasons. The total detection rate was 44. 6%. The detection rates of bile reflux, erosive gastritis, gastric polyp were > 8%. The detection rates of erosive esophagitis,stomach apophysis lesions, gastric ulcer were 3%?5%. The detection rates of lower esophagus island orange mucosa and esophagus protuberant focus, gastric yellow pigment tumor, small intestine stomach ulcer and intestinal vascular malformation were<2%. The overall abnonnal detection rate of male subjects was significantly higher than that of female subjects (51.9% vs. 32. 8%,P=0. 016), mainly with erosive gastritis. The overall abnonnal detection rate of >45 years old cases was significantly higher than that of ≤45 years old cases (54.4% vs. 33. 3%, P=0. 006). There was no significant difference in the overall abnormal detection rate between the simple physical examination group and the special cause group(42. 8% vs. 53.3%,P=0. 291). No capsules were retained in all subjects. Conclusion MCGE is safe and tolerable, with a higher detection rate of lesions in male and > 45 years old subjects, providing a basis for clinical selection of subjects and evaluation of examination results.