非酒精性脂肪性肝病的临床困境

Clinical dilemmas in non-alcoholic fatty liver disease

随着肥胖和代谢综合征在全球的流行,非酒精性脂肪性肝病已成为包括中国在内的全球肝功能异常和慢性肝病最常见的原因。该述评根据最新研究进展,讨论非酒精性脂肪性肝病的临床困境,内容涉及该病的发病机制、临床特征和自然史、疾病进展的危险因素、诊断与评估及现有治疗方法的利弊。

With global epidemic of obesity and metabolic syndrome,nonalcoholic fatty liver disease(NAFLD)has becoming the most common cause of abnormal liver tests and chronic liver disease in the world including China.The editorial is focused on the clinical dilemmas of NAFLD,with the latest and most critical information regarding the pathogenesis and nature of the condition,the factors that lead to disease progression,how best to diagnosis and assess value of currently available different treatment measures.