儿童过敏性鼻炎的特异性免疫治疗

Specific immunotherapy for allergic rhinitis in children

特异性免疫治疗(AIT)是目前惟一可能改变儿童过敏性鼻炎(AR)自然病程的治疗方法,在取得了良好临床疗效的同时减少了AR患儿的药物用量,提高了生活质量。预防AR进展到哮喘,并减少新的变应原过敏。针对AIT产生的新方法、新技术的目的是缩短达到免疫耐受的时间,提高患儿依从性,增强治疗的安全性,并尽可能的降低治疗负担。该文对AR患儿AIT临床进展进行综述。

At present,allergen-specific immunotherapy(AIT)is the only treatment method that can change the natural course of allergic rhinitis in children. While achieving good clinical efficacy,it reduces the dosage of drugs for AR children,improves the quality of life,prevents AR progression to asthma,and reduces new allergens. New methods and techniques for AIT are designed to shorten the time to reach immune tolerance,improve the compliance of children,enhance the safety of treatment,and reduce the treatment burden as much as possible. Here,we review the clinical progress of AIT in AR children.