原发性肝癌术后患者癌因性疲乏现状及影响因素分析

Study on the status of cancer-related fatigue in postoperative patients with primary liver cancer and its influencing factors

目的探讨原发性肝癌术后患者癌因性疲乏现状及其影响因素。方法采用便利抽样法,选取于2015年10月—2017年9月在哈尔滨医科大学附属第二医院接受手术治疗的原发性肝癌患者149例为研究对象。采用一般资料调查表、癌症疲乏量表(CFS)、社会支持评定量表对其进行调查。本研究共发放问卷149份,回收有效问卷为120份。结果120例肝癌患者CFS得分为(48.13±5.33)分。不同文化程度、月收入、医疗费用支付方式、病程时间、对疾病认知程度、是否化疗、社会支持度的肝癌患者CFS得分差异有统计学意义(P<0.05)。多元线性回归分析显示,医疗费用支付方式、病程时间、对疾病认知程度、辅助化疗以及社会支持度是肝癌患者癌因性疲乏的影响因素(P<0.05)。结论癌因性疲乏是肝癌术后患者普遍存在的问题,且受多种因素影响。医护人员应结合患者的实际情况,制定更有针对性的个体化方案来减轻患者癌因性疲乏状态,提高患者社会支持度,进一步改善患者生活质量。

Objective To investigate the status of cancer-induced fatigue in patients with primary liver cancer(PLC)and its influencing factors.Methods A total of 149 postoperative PLC patients undergoing surgical treatment during October 2015 to September 2017 in the Second Affiliated Hospital of Harbin Medical University were recruited by convenience sampling method.The general data questionnaire,Cancer-Related Fatigue Scale(CFS)and Social Support Rating Scale(SSRS)were used to investigate the patients.A total of 149 questionnaires were sent out and 120 valid questionnaires were collected.Results The CFS score of the 120 postoperative PLC patients was(48.13±5.33).The difference in CFS scores of PLC patients with different education level,monthly income,medical expenses payment,duration of the disease,cognition of disease,chemotherapy and social support was statistically significant(P<0.05).Multivariate linear regression analysis showed that the influencing factors of cancer-related fatigue in patients with PLC were medical expenses payment,duration of disease,cognition of disease,adjuvant chemotherapy and social support(P<0.05).Conclusions Cancer-related fatigue is a common problem in PLC patients and is affected by many factors.Clinicians need to combine with the actual situation of patients to develop more targeted individualized programs to alleviate the patient fatigue,improve patient social support,and further improve the quality of life of patients.