期刊文献+

血清SCC、CEA、CA125与CA19-9水平联合检测对早期宫颈癌患者诊断准确率的影响 被引量:12

下载PDF
导出
摘要 目的:探讨血清糖类抗原19-9(CA19-9)、CA125、癌胚抗原(CEA)、鳞状细胞癌抗原(SCC)水平联合检测对早期宫颈癌患者诊断准确率的影响。方法:选取我院2015年11月—2017年12月71例宫颈癌患者设为恶性组、71例宫颈良性病变患者设为良性组,另选取同期健康体检者71例设为对照组。抽取所有受检者空腹静脉血,经酶联免疫吸附法测定血清CA19-9、CA125、CEA、SCC水平,对比三组及恶性组不同病理类型患者血清肿瘤标志物水平,并统计CA19-9、CA125、CEA、SCC单独及联合诊断宫颈癌价值。结果:三组血清CA19-9、CA125、CEA、SCC水平间存在明显差异(P<0.05),且恶性组各指标水平高于良性组及对照组(P<0.05);腺癌患者血清CA19-9、CA125、CEA水平高于鳞癌患者,腺癌患者SCC水平低于鳞癌患者(P<0.05);联合诊断敏感度(90.14%)、准确度(93.43%)高于CA19-9、CA125、CEA、SCC(P<0.05)。结论:联合SCC、CEA、CA125、CA19-9诊断宫颈癌可提高敏感度及准确度,且利于鉴别宫颈癌病理类型。
作者 贺淑巍
出处 《现代医用影像学》 2019年第2期433-434,437,共3页 Modern Medical Imageology
  • 相关文献

参考文献8

二级参考文献50

  • 1邓湘,修霞,王德昌,侯秀玉,李高峰.CYFRA 21-1肿瘤标志物在宫颈鳞癌诊断和放疗疗效评价中的作用[J].中国临床保健杂志,2007,10(3):249-251. 被引量:5
  • 2Gadducci A,Tana R, Cosio S,et a|. The serum assay of tumormark- ers in the prognostic evaluation,treatmentm on itoring and follow-up of patients with cervical cancer[ J]. Oncology Hematology,2008,66 (1):10-20.
  • 3Lehtovirta P, Vinikka L,Ylikorkala O. Comparison between squa- mous cell carcinoma-associated antigen and CA125 in patients with carcinoma of the cervix [ J 1- Gynecol Oncol, 1990,37 ( 2 ) : 276 - 278.
  • 4Takeda M,Sakuragl N ,Okamoto K,et al. Preoperative serum S(C, CA125 ,and CA 19 -9 levels and lymphnode status in squamous cell carcinom a of the uterine cervix J 1. Acta Obstet Gynecol Scand ,2002,81 ( 5 ) :451 - 457.
  • 5Bender Dl,Sorosky JI,BuBer RE,et M. Serum CA125 is an inde- pendent prognostic factor in cervical adenocarcinoma[ J 1. Am J Ob- stet Gyneco1,2003,189( 1 ) :113 - 117.
  • 6连丽娟;林巧稚.妇科肿瘤学[M]北京:人民卫生出版社,2008288.
  • 7Hou CY,Li XL,Jiang F. Comparative evaluation of surgical stress of laparoscopically assisted vaginal radical hysterectomy and lymphadenectomy and laparotomy for early-stage cervical cancer[J].Oncol Lett,2011,(04):747.
  • 8Kucera R,Cerna M,Narsanska A. Growth factors and breast tumors,comparison of selected growth factors with traditional tumor markers[J].Anticancer Research,2011,(12):4653.
  • 9Kuroda Y,Murakami N,Morota M. Impact of concurrent chemotherapy on definitive radiotherapy for women with FIGO Ⅲb cervical cancer[J].Journal of Radiation Research,2012,(04):588.
  • 10Mabuchi S,Okazawa M,Matsuo K. Impact of histological subtype on survival of patients with surgically-treated stage IA2-(Ⅱ)B cervical cancer:Adenocarcinoma versus squamous cell carcinoma[J].Gynecologic Oncology,2012,(01):114.

共引文献149

同被引文献107

引证文献12

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部