低血糖与糖尿病心血管并发症

Hypoglycemia and diabetic cardiovascular complications

严格的血糖控制对糖尿病患者至关重要,但随之而来的低血糖不可避免地增加了心血管事件的发生风险及全因死亡率。低血糖主要通过影响血流动力学、心脏电生理,引起炎性反应及损伤凝血系统等一系列病理生理过程,诱导糖尿病患者心血管并发症的发生。探究低血糖与糖尿病心血管并发症之间的关系,并进一步阐释其可能的发病机制,可为后续研究及临床治疗提供新的思路。

Strict glucose control means significantly to patients with diabetes mellitus. However, the following hypoglycemia inevitably increases the cardiovascular events and allcause mortality. Hypoglycemia induce the diabetic cardiovascular complications through a series of changes on pathophysiological processes mainly including hemodynamics, electrophysiology, inflammation and coagulation. Explore the relationship between hypoglycemia and diabetic cardiovascular complications, then further elucidate the pathogenesis, can provide new ideas for subsequent studies and clinical treatment.