口腔黏膜幼年性黄色肉芽肿1例报告及文献复习

Oral juvenile xanthogranuloma:a case report and literature review

幼年性黄色肉芽肿是非朗格汉斯组织细胞增生症中的一种,主要发生于皮肤,可单发或多发,皮肤外器官主要累及眼、中枢神经系统、肝脏、肾脏等,口腔病变罕见。本文报告1例发生于腭部的幼年性黄色肉芽肿病例。该患儿表现为腭部黏膜下黄色结节,无明显疼痛,不影响进食及语言功能,治疗采取手术切除,术后免疫组织化学报告为幼年性黄色肉芽肿。

Juvenile xanthogranuloma(JXG) is a rare non-Langerhans cell histiocytosis that usually occurs in the skin of children, single or multiple. The systemic form of JXG affected extracutaneous sites-mostly the eyes, central nervous system, liver, kidney, etc. Oral JXG is rare. This paper reported a case with yellowish papule affecting the hard palate,without typical clinical symptoms. The lesion was surgically excised, histological and immunohistochemical analysis revealed JXG.