不同年龄段缺血性结肠炎临床特征的比较

Comparison of clinical features of ischemic colitis in different ages

目的探讨不同年龄段患者缺血性结肠炎(IC)的临床特征。方法收集115例IC患者,按照年龄<65岁、≥65岁分别设定为中青年组和老年组,比较两组人口统计学资料、既往病史、48 h内实验室指标、影像学检查、肠镜检查、住院期间病情变化、住院天数、转归等指标间的差异。结果中青年组与老年组纤维蛋白原和血钾水平比较,差异有统计学意义(P<0.05)。老年组患者高血压、冠心病、脑梗死、房颤比例较中青年组显著升高,差异有统计学意义(P<0.05)。结论中青年与老年在临床症状上无明显差异,老年组血钾水平偏低,其机体呈现更明显的高凝状态,且常患动脉粥样硬化相关合并症,尽早行肠镜检查有助于尽早诊断IC。

Objective To investigate the clinical features of ischemic colitis(IC)in different ages.Methods A total of 115 IC patients were recruited and divided into yong and middle-aged group(age<65 yeas old)and elderly group(age≥65 years old).Demographic characteristics,history of chronic diseasee,laboratory indicators,imaging examination,colonoscopy,change of condition during hospitalization,hospitalization days,outcome and other indicators were compared between two groups.Results The levels of fibrinogen and serum potassium in the young and middle-aged group were statistically significant compared with elderly group(P<0.05).The proportion of hypertension,coronary heart disease,cerebral infarction and atrial fibrillation in the elderly group were significantly higher than those in the young and middle-aged group,and the difference was statistically significant(P<0.05).Conclusion There is no significant difference in clinical symptoms between young and middle-aged group and elderly group.The serum potassium level in the elderly group is low.The elderly patients are prone to be in hypercoagulable state,and often suffer from atherosclerosis-related complications.Colonoscopy will help diagnose IC as soon as possible.