柴芍承气汤联合生长抑素辅助治疗重症急性胰腺炎效果观察

Efficacy of the Chaishao Chengqi decoction plus somatostatin in the adjuvant therapy on severe acute pancreatitis

目的:研究重症急性胰腺炎患者采取柴芍承气汤与生长抑素治疗的临床价值。方法:选择我院2016年2月-2017年8月纳入的106例重症急性胰腺炎患者,按照随机数字法分为研究组与对照组,各53例,研究组采取柴芍承气汤与生长抑素,对照组采取常规治疗,对比两组临床治疗效果。结果:研究组总有效率为92.45%,高于对照组的81.13%(P <0.05);研究组腹痛缓解、首次排便、血淀粉酶恢复以及住院时间均短于对照组(P <0.05);治疗前两组急性与慢性健康评分(APACHEⅡ)、急性胰腺炎分级评分(Balthazar CT)比较,差异无统计学意义(P> 0.05),治疗后研究组各评分均低于对照组评分(P <0.05)。结论:重症急性胰腺炎采取柴芍承气汤与生长抑素治疗效果明显,快速缓解病情,促进相关症状消退,缩短住院时间,为预后提供保障。

Objective:To study the clinical value of the Chaishao Chengqi decoction(柴芍承气汤)plus somatostatin in the adjuvant therapy on severe acute pancreatitis.Methods:106 severe acute pancreatitis patients treated from February 2016 to August 2017 in our hospital were selected.The subjects were randomly assigned to two groups,53 cases in each group.The study group took the Chaishao Chengqi decoction plus somatostatin;the control group took the conventional therapy.Results:The total effective rate in the study group(92.45%)was significantly higher than the control group(81.13%)(P<0.05);the relief time of stomachache,initial defecation time,recovery time of blood amylase and hospitalization time in the study group was shorter(P<0.05).The APACHE Ⅱ and Balthazar CT scores inthe study group were lower than control group(P<0.05).Conclusion:The Chaishao Chengqi decoction plus somatostatin can remarkably relieve the disease,promote the disappearance of symptoms,shorten the hospitalization time and improve the patient’s prognosis.