重度妊娠高血压合并HELLP综合征的临床研究

A clinical study on severe pregnancy-induced hypertension with HELLP syndrome

目的:对重度妊娠高血压合并HELLP综合征患者进行研究分析,为今后的临床诊疗工作提供有价值的参考依据。方法:选择2015年1月-2017年9月间,我院收治的获得临床确诊的重度妊娠高血压合并HELLP综合征患者48例作为研究对象,将其分成HELLPⅠ级组和Ⅱ级组,分别含有患者27例和21例,对两组患者生化指标、母婴结局进行对比分析。结果:Ⅰ级组与Ⅱ级组患者血小板(Blood Platelet,PLT)、谷丙转氨酶(ALT),谷草转氨酶(AST)检测结果比较,差异无统计学意义(P>0.05);Ⅰ级组患者乳酸脱氢酶(LDH)水平显著高于Ⅱ级组患者(P <0.05);两组产妇并发症发生率、胎儿并发症发生率比较,差异存在明显统计学意义(P <0.05)。结论:HELLP综合征属于重度妊娠高血压常见并发症,Ⅰ级组患者病情较Ⅱ级组严重,临床诊疗中应对其给予足够的重视,适时终止妊娠,降低母婴并发症发生率。

Objective:To study severe pregnancy-induced hypertension with HELLP syndrome,provide a reference for clinical treatment.Methods:From January 2015 to September 2017,48 cases were divided into 2 groups,27 cases in the groupⅠ;21 cases in the group Ⅱ.The biochemical indicators and maternal and child outcomes in two groups were analyzed.Results:There was no significant difference in PLT,ALT and AST between the two groups(P>0.05).The LDH level in group Ⅰ was significantly higher than that in group Ⅱ(P<0.05).There was a significant difference in the incidence of maternal complications and the incidence of fetal complications between the two groups(P<0.05).Conclusion:HELLP syndrome is a common complication of severe pregnancy-induced hypertension.The disease in the group Ⅰ is more severe than group Ⅱ,and should be pay more attention.If it happened,pregnancy should be terminated in time in order to reduce the incidence of maternal and child complications.