慢性肾病并发胃肠道症状的病因病机及中医研究进展

Etiology and pathogenesis of chronic kidney disease complicated with gastrointestinal symptom and advances in TCM

胃肠道症状是慢性肾病最常见的并发症,可随病情进展日益加重,影响疾病预后和患者生存质量。从西医角度论述,其发病机制主要以胃肠动力学发生改变、肾功能减退引起的胃肠激素紊乱、肾性贫血引起的胃黏膜损伤等有关,中医认为其病位在脾胃肾,以脾肾亏虚为本,湿浊血瘀内生上逆于胃为标,证属本虚标实。大量资料可证实,中医对于慢性肾病并发胃肠道症状有明显疗效,该文对慢性肾病并发胃肠道症状的病因病机及中医治法进行阐述,以期为临床治疗提供参考。

Gastrointestinal symptoms are the most common complications of chronic kidney disease,which can be aggravated with the progress of the disease,and affects the prognosis of the disease and the quality of life of the patients.From the point of view of western medicine,the pathogenesis is mainly related to the change of gastrointestinal dynamics,the disorder of gastrointestinal hormones caused by renal dysfunction,the damage of gastric mucous caused by renal anemia.Traditional Chinese medicine thinks the disease is located in the spleen,stomach and kidney,Spleen-kidney deficiency,with dampness turbid blood stasis genetic inverse stomach as the standard,syndromes belong to aesthetic in origin and aesthetic in superficiality.A large number of data can confirm that TCM has obvious curative effect on chronic kidney disease complicated with gastrointestinal symptoms.This article expounds the etiology and pathogenesis of chronic kidney disease complicated with gastrointestinal symptoms and TCM treatment in order to provide reference for clinical practice.