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辛伐他汀联合替格瑞洛对急性冠脉综合征患者PCI术后心肌灌注的影响 被引量:1

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摘要 目的探究辛伐他汀联合替格瑞洛对急性冠脉综合征患者经皮冠状动脉介入术(PCI)后心肌灌注的影响。方法选择2015年3月至2017年3月我院112例行PCI术的急性冠脉综合征患者,按随机数字表法分为观察组(n=56)及对照组(n=56)。常规治疗基础上,对照组PCI术前予以辛伐他汀治疗,观察组PCI术前予以辛伐他汀联合替格瑞洛治疗,并于术后予以替格瑞洛治疗。对比两组治疗后TIMI心肌灌注分级、心血管不良事件与出血并发症发生情况。结果观察组治疗后TIMI心肌灌注分级优于对照组(P<0.05);观察组心血管不良事件及并发症发生率与对照组比较,无显著差异(P>0.05)。结论对行PCI术的急性冠脉综合征患者应用辛伐他汀联合替格瑞洛治疗可有效改善患者心肌灌注情况,且安全性良好。
出处 《海峡药学》 2019年第3期160-161,共2页 Strait Pharmaceutical Journal
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