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药物涂层球囊在冠状动脉介入治疗中的应用 被引量:7

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摘要 随着冠状动脉支架置入术逐渐普及,冠状动脉支架置入后带来的支架内再狭窄(in stent restenosis,ISR)、金属支架永久留在体内、术后双联抗血小板治疗并发症等问题也愈发严重,即使应用药物洗脱支架(drug-eluting stents,DES)治疗仍无法很好解决慢性完全闭塞病变(chronic total occlusion,CTO)、冠脉小分支病变、冠脉弥漫性狭窄、冠脉血管严重扭曲病变、冠状动脉桥血管吻合口病变等问题。一些特殊的复杂冠状动脉病变如:冠脉小分支病变、冠脉弥漫性狭窄、冠脉血管严重扭曲病变、冠状动脉桥血管吻合口病变等并不适合置入支架或支架置入存在严重的困难,随着药物涂层球囊(drug coated balloon,DCB)问世,其在冠脉介入领域的作用日益突出,DCB具有不存在金属置入物、术后双联抗血小板治疗时间短的特点,为冠状动脉粥样硬化性心脏病的治疗提供新的方法。本文就DCB作用机制及在冠状动脉介入治疗中的应用进行综述。
出处 《河南医学研究》 CAS 2019年第6期1150-1151,共2页 Henan Medical Research
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