脑立清丸中猪胆粉的专属性检查研究

Study on the Specificity Test of Pig Bile Powder in Naoliqing Pills

目的:2015版《中国药典》标明脑立清丸中猪胆粉不应有牛、羊胆的鉴别特征。本研究通过对脑立清丸水解前后与牛、羊胆进行薄层鉴别对比,试图建立脑立清丸中不应有牛、羊胆的快速检查方法。结果:本实验对十二个厂家的粉末进行牛、羊胆试验,结果无一家生产企业有牛、羊胆的特征,说明十二家企业原料中均未掺有牛、羊胆现象。结论:薄层鉴别法更加简便,快捷,经济,解决了现行质量标准不能控制以牛、羊胆代替猪胆加工猪胆粉的问题。

Objective: The 2015 edition of “Pharmacopoeia” marked China Naoliqing pills in porcine bile powder should not have the distinguishing characteristics of cattle and sheep bile. This study by the TLC comparison of Naoliqing pills before and after hydrolysis with cattle and sheep bile, trying to quickly establish a test method of Naoliqing pills should not have cattle and sheep bile. Methods: In this experiment, twelve manufacturers of powder for cattle and sheep bile test, the results of no production enterprises have cattle, sheep bile characteristics, indicating that twelve enterprises raw materials are not mixed with cattle, sheep bile phenomenon. Results: The TLC identification method is more convenient, quick and economical, and solves the problem that the current quality standard can not control the pig bile powder with ox and sheep bile instead of pig bile.