早期胃癌内镜下黏膜剥离术与常规手术对比及患者2年期复发率分析

Comparison Between Endoscopic Mucosal Dissection and Conventional Surgery and 2-year Recurrence Rate in Patients with Early Gastric Cancer

目的:对比内镜下黏膜剥离术与常规手术治疗早期胃癌患者的效果以及2年复发率。方法:选取2014年12月-2016年12月本院收治的早期胃癌患者94例。按照随机数字表法将其分为观察组和对照组,各47例。对照组予以常规手术治疗,观察组则予以内镜下黏膜剥离术治疗。比较两组各项手术指标水平、术后并发症发生情况、临床疗效以及术后1、2年复发率。结果:观察组手术时间、术中出血量、抗菌药物使用时间、住院时间、住院费用均少于对照组,差异均有统计学意义(P<0.05);观察组术后穿孔发生率以及并发症发生率均高于对照组,差异均有统计学意义(P<0.05);两组整块切除率、治愈性切除率以及术后1、2年复发率比较,差异均无统计学意义(P>0.05)。结论:内镜下黏膜剥离术治疗早期胃癌效果更佳且有利于促进患者术后早日康复,降低术后并发症发生风险的同时不会增加术后复发率。

Objective:To compare the efficacy of endoscopic mucosal dissection and conventional surgery in treatment of early gastric cancer patients and the 2-year recurrence rate.Method:A total of 94 patients with early gastric cancer admitted to our hospital from December 2014 to December 2016 were selected.According to the random number table method,they were divided into observation group and control group,47 cases in each group.The control group was treated with conventional surgery,while observation group was treated with endoscopic mucosal dissection.The levels of surgical indicators,the occurrence of complications,clinical efficacy and the recurrence rate in 1 or 2 years after operation between two groups were compared.Result:The operation time,intraoperative bleeding volume,antimicrobial use time,hospitalization time and hospitalization expenses of observation group were less than those of control group,the differences were statistically significant(P<0.05).The incidences of perforation and complications in observation group were higher than those of control group,the differences were statistically significant(P<0.05).The rates of total excision,curative excision and recurrence 1 or 2 years after operation in two groups were compared,the differences were noy statistically significant(P>0.05).Conclusion:Endoscopic mucosal dissection is more effective in treatment of early gastric cancer,which is conducive to the early postoperative recovery of patients,reduces the risk of postoperative complications,and does not increase the rate of postoperative recurrence.