甲泼尼龙联合阿奇霉素治疗儿童支原体肺炎效果

The Effect of Methylprednisolone and Azithromycin on Children With Mycoplasmal Pneumonia

目的评价甲泼尼龙联合阿奇霉素治疗儿童支原体肺炎的效果。方法选取我院2018年1—9月收治的儿童支原体肺炎患儿106例作为研究对象。依据随机数表分组方式,将其分为对照组、考察组,每组各53例。两组患者分别予以阿奇霉素、甲泼尼龙联合阿奇霉素治疗,综合评价联合用药方案的应用价值。结果考察组患儿咳嗽、发热、肺部啰音等症状消失时间及住院时间均短于对照组,组间各数据对比,差异具有统计学意义(P <0.05)。考察组不良反应发生率(5.66%)与对照组(3.77%)对比,差异无统计学意义(P> 0.05)。结论甲泼尼龙联合阿奇霉素治疗儿童支原体肺炎,能够缩短患儿的症状改善时间、住院时间,快速改善病情,促进康复,且不会增加不良反应,效果及安全性俱佳,故判断此种治疗方案具有良好应用价值。

Objective To evaluate the efficacy of methylprednisolone combined with azithromycin in the treatment of mycoplasma pneumonia in children.Methods 106 children with mycoplasma pneumonia admitted to our hospital from January to September 2018 were selected as the research objects.According to the grouping method of random number table,the patients were divided into control group and investigation group,53 cases in each group.The two groups were treated with azithromycin,methylprednisolone and azithromycin respectively,and the application value of the combination regimen was evaluated comprehensively.Results The disappearance time and hospitalization time of cough,fever,lung rale and other symptoms in the observation group were shorter than those in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the study group(5.66%)and the control group(3.77%)(P>0.05).Conclusion Methylprednisolone combined with azithromycin in the treatment of children with mycoplasmal pneumonia can shorten the symptom improvement time and hospitalization time of the child,rapidly improve the condition and promote rehabilitation,and will not increase the adverse reactions,and the effect and safety are good.Therefore,the treatment is judged.