早期胃癌术后相对严重并发症的临床特点和危险因素分析

Analysis of clinical characteristics and risk factors of relatively serious complications of early gastric cancer after operation

目的探讨早期胃癌(EGC)术后出现相对严重并发症的临床特点和危险因素。方法回顾性分析2016年3月—2017年3月南昌大学第一附属医院收治的114例经术后病理证实为EGC患者的临床资料,按照术后有无出现相对严重并发症分为有并发症组(16例)和无并发症组(98例)。对各临床指标和术后相关指标等对EGC患者术后是否出现相对严重并发症进行单因素分析,应用Logistic回归多因素分析筛查EGC术后发生相对严重并发症的独立危险因素。结果 EGC男女发病比例为1.92∶1.00,术后出现并发症的患者平均年龄高于无并发症患者的平均年龄(P <0.05);单因素分析显示,年龄和术前合并高血压是EGC术后出现相对严重并发症的危险因素(P <0.05);多因素Logistic回归分析显示,年龄是其独立危险因素(P <0.05)。结论年龄≥60岁或术前合并高血压的EGC患者术后出现相对严重并发症的风险高。

Objective To investigate clinical characteristics and risk factors of postoperative relatively serious complications in early gastric cancer(EGC).Methods Totally 114 early gastric cancer patients confirmed by postoperative pathology in the First Affiliated Hospital of Nanchang University from March 2016 to March 2017 were enrolled in this study.The patients were divided into complication group(16 cases)and no complication group(98 cases)according to whether or not there were postoperative relatively serious postoperative complications.Univariate analysis was performed on the various clinical indicators and related indicators of complications in patients with early gastric cancer,and the independent risk factors were determined by Logistic regression analysis.Results The incidence of EGC is 1.92:1.00 in men and women;the mean age of patients with postoperative complications was greater than that of patients without complications(P<0.05);univariate analysis revealed that age and preoperative hypertension were risk factors of relative serious complications for the early gastric cancer(P<0.05);multivariate Logistic regression analysis revealed that age was independent risk factors of postoperative relative serious complications for the early gastric cancer(P<0.05).Conclusions Patients with early gastric cancer who are over 60 years or have hypertensive have high risk of relatively severe complications.