冻融胚胎移植自发性卵巢过度刺激综合征1例和文献综述

A case report and literature review of spontaneous ovarian hyperstimulation syndrome

目的探讨自然周期冻融胚胎移植妊娠后发生自发性卵巢过度刺激综合征(sOHSS)的机理及处理措施。方法对1例自然周期冻融胚胎移植妊娠发生sOHSS的诊断及治疗过程进行报道并对相关病例资料进行回顾分析。结果本文患者自然周期冻融胚胎移植妊娠后发生sOHSS是首例报道并成功分娩。结论sOHSS是一种罕见病,发病机理尚无定论,sOHSS会影响胚胎发育和胎儿成活率,病情严重者可能危及生命应引起高度关注。

Objective To explore the mechanism and treatment of spontaneous ovarian hyperstimulation syndrome (sOHSS) after natural cycle frozen-thawed embryo transfer pregnancy. Methods We reported and reviewed the diagnosis and treatment of a patient carrying intrauterine pregnancy combined with sOHSS in the natural cycle freeze-thawed embryo transfer. Result This patient with sOHSS was the first case reported and successfully delivered after natural cycle frozen-thawed embryo transfer. Conclusion sOHSS is a rare disease, and may affect embryo development and fetal survival rate. Its pathogenesis is still unknown. Serious cases may be life-threatening and should be closely monitored.