艾地苯醌联合正念疗法对卒中后抑郁临床疗效分析

Analysis of the clinical efficacy of aldibenzoquinone combined with mindfulness therapy in the treatment of post-stroke depression

目的:对艾地苯醌联合正念疗法治疗脑卒中后抑郁的临床疗效分析。方法:将脑梗死后抑郁患者165例随机分成对照组(80例)和艾地苯醌联合正念组(85例),对照组给予神经内科常规治疗及心理治疗,艾地苯醌联合正念组在此基础上加用艾地苯醌和正念疗法。分别于治疗前、治疗后4周对两组患者进行汉密尔顿抑郁量表评分(HAMD)、神经功能缺损程度评分(SSS)和疗效评定。结果:艾地苯醌联合正念组抗抑郁疗效及神经功能康复疗效均优于对照组,差异有统计学意义(P<0.05)。结论:艾地苯醌联合正念对脑卒中后抑郁有较好的疗效,并能促进神经功能的恢复。

Objective:To analyze the clinical efficacy of aldibenzoquinone combined with mindfulness therapy in the treatment of post-stroke depression.Methods:165 patients with depression after cerebral infarction were randomly divided into the control group with 80 cases and the aldibenzoquinone group with 84 cases.The control group was given routine treatment and psychotherapy.The aldibenzoquinone and mindfulness group was treated with aldibenzoquinone combined with mindfulness therapy on this basis.The Hamilton Depression Scale(HAMD),Neurofunctional Deficiency Scale(SSS)and curative effect evaluation were performed on the two groups before and 4 weeks after treatment.Results:The antidepressant effect and neurofunctional rehabilitation effect of the adibenzoquinone combined with mindfulness group were better than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:Adibenzoquinone combined with mindfulness thought has a good effect on post-stroke depression and can promote the recovery of nerve function.