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心理干预联合个体化营养管理对肿瘤化疗患者心理健康及生活质量的影响 被引量:23

Effect of psychological intervention combined with individualized nutrition management on mental health status and quality of life of cancer patients receiving chemotherapy
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摘要 目的探索心理干预联合个体化营养管理对肿瘤化疗患者心理健康及生活质量的影响。方法选取120例肿瘤化疗患者,根据干预方法分为观察组(常规卫生宣教加心理干预联合个体化营养管理)60例和对照组(常规卫生宣教)60例。采用汉密尔顿焦虑评分量表(HAMA)、汉密尔顿抑郁评分量表(HAMD)、简明心境量表(BPOMS)、生活质量量表(QLQ-C30)评估两组患者化疗前后的情绪及生活质量等,并通过Log-rank检验分析两组患者的生存情况。结果化疗前,两组患者的HAMA、HAMD、BPOMS、QLQ-C30各项评分比较,差异均无统计学意义(P﹥0.05);化疗后,两组患者的HAMA、HAMD、紧张-焦虑、抑郁-沮丧、发怒-敌视、疲劳-迟钝、慌乱-迷惑评分均低于本组化疗前(P﹤0.05),且观察组上述各项评分均低于对照组(P﹤0.05);化疗后,两组患者的精力-活动、身体功能、生理功能、心理功能、社会功能评分均高于本组化疗前(P﹤0.05),且观察组上述各项评分均明显高于对照组(P﹤0.01)。随访1年,观察组患者死亡21例,对照组患者死亡25例;Log-rank检验结果显示,观察组患者的生存情况优于对照组(P﹤0.05)。结论与常规卫生宣教比较,心理干预联合个体化营养管理可以改善患者的不良情绪和心理状况,提高生活质量。 Objective To explore the effects of psychological intervention combined with individualized nutrition management on the mental health status and quality of life of cancer patients receiving chemotherapy.Method A total of 120 cancer patients treated with chemotherapy were allocated as study group (conventional healthcare education + psychological intervention + individualized nutrition management,n=60) and control group (conventional healthcare education, n=60) according to different intervention methods.The Hamilton anxiety rating scale (HAMA),Hamilton depression ratingscale (HAMD),brief profile of mood state (BPOMS) and quality of life questionnaire core 30 (QLQ-C30) were used to compare the mood and quality of life between the two groups before and after chemotherapy,and Log-rank test was utilized to evaluate the survival of these patients.Result Before chemotherapy,the HAMA,HAMD,BPOMS,QLQC30 scores were similar in both groups,with no statistically significant differences observed (P>0.05);after chemotherapy, scores including HAMA,HAMD,tension or anxiety,depression or dejection,anger or hostility,fatigue or inertia,and confusion or bewilderment were decreased in the two groups (P<0.05),and those in study group were lower than those in control group (P<0.05);after chemotherapy,the vigor or activity,physical function,physiological function,psychological function,social function scores were higher in both groups compared with before treatment (P<0.05),and those in study group were significantly higher in comparison with those in control group (P<0.01).During the 1-year follow-up,there were 21 deaths in the study group and 25 in the control group;the Log-rank test indicated a better overall survival in study group compared with control group (P<0.05).Conclusion Compared with conventional healthcare education,psychological intervention combined with individualized nutrition management can improve the negative emotions and psychological conditions and ameliorate the quality of life for patients receiving chemotherapy.
作者 吴倩 王秋杰 金融 WU Qian;WANG Qiujie;JIN Rong(Emergency Department,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)
出处 《癌症进展》 2019年第7期865-868,共4页 Oncology Progress
关键词 心理干预 个体化营养管理 肿瘤 化疗 心理健康 生活质量 psychological intervention individualized nutrition management tumor chemotherapy mental health quality of life
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