盐酸奥布卡因凝胶联合氯诺昔康在缓解膀胱镜检查中疼痛的临床研究

Clinical study of Oxybuprocaine hydrochloride gel combined with Lornoxicam in relieving pain during cystoscopy

目的观察盐酸奥布卡因凝胶联合氯诺昔康对膀胱镜检查所致疼痛的缓解效果。方法选取我院2017年7月—2018年12月期间接收的需要进行膀胱镜检查的60例患者,随机分为治疗组与对照组,每组30例。治疗组给予盐酸奥布卡因凝胶联合氯诺昔康,对照组则给予2%利多卡因进行治疗,对比2组患者的应激指标情况、疼痛缓解效果以及不良反应发生情况。结果治疗组患者的心率、肾上腺素、去甲肾上腺素等应激指标均明显低于对照组(P<0.05);治疗组患者术中VAS评分结果明显优于对照组(P<0.05);2组患者均未见明显不良反应。结论在膀胱镜检查过程中患者可出现较为剧烈的疼痛,采用盐酸奥布卡因凝胶联合氯诺昔康能够较好地缓解患者的疼痛感,改善相关应激指标,且无明显副作用,值得临床推广应用。

Objective To observe the efficacy of Oxybuprocaine Hydrochloride Gel combined with lornoxicam in relieving pain caused by cystoscopy and to explore its clinical value. Methods 60 patients who needed cystoscopy in our hospital from July 2017 to December 2018 were randomly selected. 60 patients were divided into routine treatment group and control group by random lottery,30 cases in each group. The conventional treatment group was treated with Oxybuprocaine Hydrochloride Gel combined with lornoxicam,while the control group was given 2% lidocaine. The stress index,pain relief effect and adverse reactions were compared between the two groups. Results Heart rate,adrenaline and norepinephrine stress index of patients in routine treatment group were significantly lower than those in control group(P<0.05);VAS score of patients in routine treatment group was significantly better than those in control group(P<0.05);adverse reactions were not observed in both groups. Conclusion In the process of cystoscopy,patients can have more severe pain. The treatment of Oxybuprocaine Hydrochloride Gel combined with lornoxicam can relieve pain and improve the related stress indicators.